This report lists the winners of Subject Certificate of Excellence awards (formerly Certificate of Distinction awards) in 2022, along with the school that they attended.
These awards are granted by the School Curriculum and Standards Authority to the top 0.5% of students in each tertiary entrance subject based on their examination marks.
Special Subject Certificates of Excellence may be awarded to a student who is ineligible for a Subject Certificate of Excellence but who has otherwise satisfied all other requirements for the award.
| 1 | Accounting and Finance | Subject Cert of Excellence | Charlton, Sophia | All Saints College | Willetton |
| 2 | Accounting and Finance | Subject Cert of Excellence | Helberg, Christian | Hale School | Wembley Downs |
| 3 | Accounting and Finance | Subject Cert of Excellence | Riley, Ella | Shenton College | Shenton Park |
| 4 | Accounting and Finance | Subject Cert of Excellence | Vescio, Jarrad | Corpus Christi College | Willetton |
| 5 | Applied Information Technology | Subject Cert of Excellence | Jong, Patrick | Chisholm Catholic College | Inglewood |
| 6 | Applied Information Technology | Subject Cert of Excellence | Not For Publication | Fountain College | Ferndale |
| 7 | Biology | Subject Cert of Excellence | Burbridge, Mackenzie | St Marys Anglican Girls School | Karrinyup |
| 8 | Biology | Subject Cert of Excellence | Cilliers, Kloe | Quinns Baptist College | Quinns Rocks |
| 9 | Biology | Subject Cert of Excellence | Delroy, Holly | Penrhos College | Como |
| 10 | Biology | Subject Cert of Excellence | Embry, Amelie | St Marys Anglican Girls School | Karrinyup |
| 11 | Biology | Subject Cert of Excellence | Fung, Ella | Perth Modern School | Subiaco |
| 12 | Biology | Subject Cert of Excellence | Lai, Chantel | Rossmoyne Senior High School | Rossmoyne |
| 13 | Biology | Subject Cert of Excellence | Not For Publication | Halls Head College | Halls Head |
| 14 | Biology | Subject Cert of Excellence | Soucik, Jade | All Saints College | Willetton |
| 15 | Biology | Subject Cert of Excellence | Stoddart, Matilda | St Hildas Anglican School for Girls | Mosman Park |
| 16 | Business Management and Enterprise | Special Subject Cert of Excellence | Ahmed Radzif, Nur Hana | Sunway College | Malaysia |
| 17 | Business Management and Enterprise | Subject Cert of Excellence | Fosu-Nyarko, Kofi | Willetton Senior High School | Willetton |
| 18 | Business Management and Enterprise | Subject Cert of Excellence | Kim, Daniel | Willetton Senior High School | Willetton |
| 19 | Business Management and Enterprise | Subject Cert of Excellence | Slack, Crawford | OneSchool Global WA | Willetton |
| 20 | Career and Enterprise | Subject Cert of Excellence | Doverty, Rebecca | Rossmoyne Senior High School | Rossmoyne |
| 21 | Career and Enterprise | Subject Cert of Excellence | Olukolu, Kelvin | Rossmoyne Senior High School | Rossmoyne |
| 22 | Chemistry | Special Subject Cert of Excellence | Kwon, Jaehyun | Applecross Senior High School | Ardross |
| 23 | Chemistry | Special Subject Cert of Excellence | Pham, Huu Trung | Mount Lawley Senior High School | Mount Lawley |
| 24 | Chemistry | Special Subject Cert of Excellence | Shi, Xiaohan | St Hildas Anglican School for Girls | Mosman Park |
| 25 | Chemistry | Subject Cert of Excellence | Chen, Caroline | Presbyterian Ladies College | Peppermint Grove |