This is the SACE Honour Roll, listing every award, merit or prize won by South Australian SACE students in 2021, along with their school and subject details.
The report also includes significant Australian national awards and prizes such as the Australian Student Prize.
| 746 | Meda, Aaditya Dhandapani | SA | Merit | Integrated Learning A | |
| 747 | Menadue, Keeley | SA | Merit | Integrated Learning B | |
| 748 | Menadue, Keeley | SA | Merit | Research Project B | |
| 749 | Menadue, Keeley | Xavier College Gawler Belt Campus | Gawler Belt | Gov of SA SACE Award | |
| 750 | Mennillo, Isabella Audrey | SA | Merit | Biology | |
| 751 | Mennillo, Isabella Audrey | SA | Merit | English | |
| 752 | Mennillo, Isabella Audrey | SA | Merit | Psychology | |
| 753 | Merchant, Eloise | SA | Merit | Workplace Practices B | |
| 754 | Meurant, Eleanor | SA | Merit | English | |
| 755 | Meurant, Eleanor | SA | Merit | Research Project B | |
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| 756 | Middleton, Abby | SA | Merit | Research Project B | |
| 757 | Middleton, Zali | SA | Merit | General Mathematics | |
| 758 | Miles, Ethan Cooper | SA | Merit | English | |
| 759 | Millar, Kaitlyn Chelsea | SA | Merit | English Literary Studies | |
| 760 | Millar, Kaitlyn Chelsea | SA | Merit | General Mathematics | |
| 761 | Miller, Rose | SA | Merit | General Mathematics | |
| 762 | Milton, Jasmine | Concordia College | Highgate | Prize: Don Maynard Music Prize | Music |
| 763 | Min, Alice Soklee | SA | Merit | Research Project B | |
| 764 | Minagall, Paige | SA | Merit | Research Project B | |
| 765 | Mitchell, Kern Lee | SA | Merit | Material Solutions | |
| 766 | Mohamed Azmi, Muhammad Hariz | SA | Merit | Research Project B | |
| 767 | Molony, Liza Rose | SA | Merit | English | |
| 768 | Montes, Annabel Lucy | SA | Merit | General Mathematics | |
| 769 | Moore, Charlotte Amy | SA | Merit | Food and Hospitality | |
| 770 | Moore, Madeline | SA | Merit | General Mathematics | |
| 771 | Moreau, Sienna | SA | Merit | Biology | |
| 772 | Morelli, Charlotte | SA | Merit | Food and Hospitality | |
| 773 | Morrissy, Ellie | SA | Merit | Religion Studies | |
| 774 | Mortimer, James Keating | SA | Merit | Media Studies | |
| 775 | Moss, Madeleine | Walford Anglican School for Girls | Hyde Park | Gov of SA SACE Award | |
| 776 | Moss, Madeleine Jemima | SA | Merit | English Literary Studies | |
| 777 | Moss, Madeleine Jemima | SA | Merit | Mathematical Methods | |
| 778 | Moss, Madeleine Jemima | SA | Merit | Physics | |
| 779 | Moukachar, Giselle | SA | Merit | Research Project B | |
| 780 | Muir, Georgia Mary | SA | Merit | Physical Education | |
| 781 | Muir, Sarah Louise | SA | Merit | Physical Education | |
| 782 | Mukherjee, Devika Kim | SA | Merit | Philosophy | |
| 783 | Mulvany, Olivia Elizabeth | SA | Merit | Outdoor Education | |
| 784 | Munir, Liam Zain | SA | Merit | Physics | |
| 785 | Munro, Rebekah Grace | SA | Merit | Modern History | |
| 786 | Muralikumar, Sankalp | SA | Merit | Mathematical Methods | |
| 787 | Muralikumar, Sankalp | SA | Merit | Physics | |
| 788 | Murphy, Ryan Benjamin | SA | Merit | Psychology | |
| 789 | Murphy, Ryan Benjamin | SA | Merit | Research Project B | |
| 790 | Murray, Isabell Grace | Henley High School | Henley Beach | Prize: Hardwicke College Prize | Biology |
| 791 | Murray, Isabella Grace | SA | Merit | Biology | |
| 792 | Murray, Isabella Grace | SA | Merit | Chemistry | |
| 793 | Murugan, Dhaanya | SA | Merit | Child Studies | |
| 794 | Musolino, Natalie | SA | Merit | Information Processing and Publishing | |
| 795 | Mutze, Sacha Rose | SA | Merit | General Mathematics | |