This is the SACE Honour Roll, listing every award, merit or prize won by South Australian SACE students in 2021, along with their school and subject details.
The report also includes significant Australian national awards and prizes such as the Australian Student Prize.
| 1068 | So, Nok Ching | SA | Merit | English as an Additional Language | |
| 1069 | Soden, Leith | SA | Merit | Mathematical Methods | |
| 1070 | Soe, Khin Thidagu Kyaw (Caroline) | SA | Merit | General Mathematics | |
| 1071 | Solding, Mereki | SA | Merit | Industry and Entrepreneurial Solutions | |
| 1072 | Somido, Arabella | SA | Merit | English | |
| 1073 | Sood, Ishani | SA | Merit | English | |
| 1074 | Sood, Ishani | SA | Merit | Legal Studies | |
| 1075 | Soontiens, Wian | SA | Merit | English | |
| 1076 | Soontiens, Wian | SA | Merit | Psychology | |
| 1077 | Soontiens, Wian | SA | Merit | Research Project B | |
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| 1078 | South, Ella | SA | Merit | Information Processing and Publishing | |
| 1079 | South, Ella | SA | Merit | Research Project A | |
| 1080 | Soutter, Miette Carmelina | SA | Merit | Business Innovation | |
| 1081 | Spajic, Anna | SA | Merit | Health and Wellbeing | |
| 1082 | Spartalis, Lily-Rose | SA | Merit | Physical Education | |
| 1083 | Spillane, Paris Bailey | SA | Merit | Health and Wellbeing | |
| 1084 | Spinelli, Eloisa | SA | Merit | English | |
| 1085 | Sprudzans, Elza Sofija | SA | Merit | Visual Arts - Art | |
| 1086 | Spyker, Lily | SA | Merit | Biology | |
| 1087 | Spyrou, Thomas | SA | Merit | Modern Greek (Continuers) | |
| 1088 | Spyrou, Thomas | SA | Merit | Research Project B | |
| 1089 | Srivastava, Tanvi | SA | Merit | Research Project B | |
| 1090 | Stafford, Nathan | SA | Merit | Creative Arts | |
| 1091 | Stafford, Nathan | SA | Merit | Research Project B | |
| 1092 | Stallard, Taylah | SA | Merit | Research Project B | |
| 1093 | Stamatelopoulo, Zoi | SA | Merit | Religion Studies | |
| 1094 | Stamatelopoulo, Zoi | SA | Merit | Research Project B | |
| 1095 | Stark, Caitlin | SA | Merit | Material Solutions | |
| 1096 | Stark, Caitlin | SA | Merit | Visual Arts - Design | |
| 1097 | Starr, Erin | SA | Merit | Business Innovation | |
| 1098 | Starr, Ned Matthew Ravi | SA | Merit | Research Project B | |
| 1099 | Stephens, Zack | SA | Merit | Modern History | |
| 1100 | Stevens, Jordan Elise | SA | Merit | Research Project B | |
| 1101 | Stock, Isabella Elsie | SA | Merit | Tourism | |
| 1102 | Stone, Rachael | SA | Merit | Biology | |
| 1103 | Stopford, Zoe | SA | Merit | English | |
| 1104 | Stracci, Jazzlin Marie Adele | SA | Merit | English | |
| 1105 | Subba, Trishna | SA | Merit | Language and Culture | |
| 1106 | Sudhir, Anushka | SA | Merit | English | |
| 1107 | Suica, Melita Rose | SA | Merit | Food and Hospitality | |
| 1108 | Sutton, Olivia | SA | Merit | Material Solutions | |
| 1109 | Swaffer, Jett | SA | Merit | English | |
| 1110 | Swaffer, Jett | SA | Merit | Physical Education | |
| 1111 | Swallowe, Alfie Benjamin | SA | Merit | General Mathematics | |
| 1112 | Swan, Tiana | SA | Merit | Research Project B | |
| 1113 | Swinburne, Lydia Ruth | SA | Merit | Modern History | |
| 1114 | Switajewski, Sophia Anne | SA | Merit | Mathematical Methods | |
| 1115 | Switajewski, Sophia Anne | SA | Merit | Research Project B | |
| 1116 | Sydney-Jones, Erin | SA | Merit | English | |
| 1117 | Symonds, Skye | SA | Merit | Music Performance - Solo | |